{"id":238,"date":"2016-04-07T22:05:26","date_gmt":"2016-04-07T22:05:26","guid":{"rendered":"https:\/\/sites.wp.odu.edu\/VisionLab\/?page_id=238"},"modified":"2023-05-26T04:25:36","modified_gmt":"2023-05-26T04:25:36","slug":"modeling-and-fusion-of-atlas-based-tumor-growth-and-feature-based-models-for-normal-and-abnormal-brain-tissue-segmentation","status":"publish","type":"page","link":"https:\/\/sites.wp.odu.edu\/VisionLab\/research\/modeling-and-fusion-of-atlas-based-tumor-growth-and-feature-based-models-for-normal-and-abnormal-brain-tissue-segmentation\/","title":{"rendered":"Modeling and Fusion of Atlas-Based Tumor Growth and Feature-Based Models for Normal and Abnormal Brain Tissue Segmentation"},"content":{"rendered":"<p>The project focuses on accurate segmentation of different tissue types including tumor and other abnormalities in the brain. Due to tumors&#8217; highly diffusive and infiltrative nature, it is difficult to distinguish tumor from healthy brain tissue. Simulation of tumor growth based on mathematical models can provide reasonable prediction of tumor trajectory in longitudinal brain studies. A model based on cell proliferation and diffusion has been developed to use for simulating the tumor growth. To improve the quality of simulation, we will study novel information theoretic models to fuse atlas-based mathematical tumor growth to our feature-based techniques for improved segmentation of normal and abnormal brain tissues.<br \/> <a href=\"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-content\/uploads\/sites\/1499\/2023\/05\/day1.jpg\" rel=\"attachment wp-att-240\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-240\" src=\"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-content\/uploads\/sites\/1499\/2023\/05\/day1.jpg\" alt=\"tcia_pat396_t1c_77_day1\" width=\"300\" height=\"300\"><\/a><br \/> Figure 1. Tumor in T1C modality of a patient<br \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-239\" src=\"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-content\/uploads\/sites\/1499\/2023\/05\/day263.jpg\" alt=\"tcia_pat396_t1c_77_day105\" width=\"300\" height=\"300\"><br \/> Figure 2. Simulation of tumor growth after 263 days tumor seed growing based on Expectation-Maximization algorithm<\/p> <p>This project is partially sponsored by and\/or in collaboration with the following:<a href=\"http:\/\/nih.gov\/\">NIH<\/a>, <a href=\"http:\/\/www.rad.upenn.edu\/sbia\/personnel.html\">Section of Biomedical Image Analysis,UPenn<\/a><\/p> ","protected":false},"excerpt":{"rendered":"<p>The project focuses on accurate segmentation of different tissue types including tumor and other abnormalities in the brain. Due to tumors&#8217; highly diffusive and infiltrative nature, it is difficult to distinguish tumor from healthy brain tissue. Simulation of tumor growth based on mathematical models can provide reasonable prediction of tumor trajectory in longitudinal brain studies. [&hellip;]<\/p>\n","protected":false},"author":5165,"featured_media":0,"parent":35,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/pages\/238"}],"collection":[{"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/users\/5165"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/comments?post=238"}],"version-history":[{"count":4,"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/pages\/238\/revisions"}],"predecessor-version":[{"id":2352,"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/pages\/238\/revisions\/2352"}],"up":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/pages\/35"}],"wp:attachment":[{"href":"https:\/\/sites.wp.odu.edu\/VisionLab\/wp-json\/wp\/v2\/media?parent=238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}