Learning about antibodies in Immunology, particularly IgE, helped me form a connection to another class that I was also taking, Biochemistry. In that course, we were assigned to research Alpha-Gal syndrome and how the allergy forms in humans. Alpha-Gal, a carbohydrate found in red meat, can be introduced into the body through a Lone Star tick bite. Since the human body does not naturally produce alpha-gal, the immune system will recognize it as a foreign substance and will create antibodies to fight it. During the research, I learned that IgE is the antibody responsible for mediating these allergic responses. Understanding this, the IgE antibodies can persist in the body and can activate later on when red meat is consumed. Already knowing the basis of antibodies, it made it easier for me to grasp the syndrome and how the carbohydrate can affect the human body.
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