Carter et al.’s study is a primary, peer-reviewed research article that was published in the Journal of Allergy and Clinical Immunology, one of many respected scientific journals. This article can be classified as a primary article because it provides original data collected by the authors through clinical testing and genetic analysis. There are sections that make this a primary research paper. An introduction, which provides background on idiopathic anaphylaxis and mast cell
disorders, along with a clear statement of the research objectives. A methods section, which details the techniques used in the study, such as patient enrollment, allele-specific PCR for the KIT D816V mutation, bone marrow biopsies, mast cell cultures, and statistical analyses. Then, there is a results section which presents the data gathered from these experiments, including the genetic findings and biomarker profiles. Lastly, there is a discussion section that interprets the findings in the context of mast cell disease and idiopathic anaphylaxis. By including original data, figures, and tables, it supports its classification as a primary article. Additionally, since it is published in a peer-reviewed scientific journal, the article has undergone evaluation by experts in the field to ensure the accuracy and validity of the paper, which in turn confirms its peer-reviewed status.

Citation:
Carter, M.C. et al. A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis. J. Allergy Clin. Immunol. 141, 180-188.e3; https://doi.org/10.1016/j.jaci.2017.05.036 (2018).