This diagram illustrates the structure of the membrane-bound IgM (B-cell receptor). The antigen-recognition Fab regions, including the variable regions, extend outward to interact with antigens. The constant regions provide structural stability and aid in signal transduction. The receptor is anchored… Continue Reading →

Trastuzumab, also known as Herceptin, is a monoclonal antibody used to treat HER2-positive breast cancer and certain types of stomach cancer (National Cancer Institute, n.d.). HER2-positive breast cancer occurs when cells produce too much human epidermal growth factor receptor 2… Continue Reading →