{"id":194,"date":"2025-05-02T22:04:18","date_gmt":"2025-05-02T22:04:18","guid":{"rendered":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/?p=194"},"modified":"2025-05-02T22:15:09","modified_gmt":"2025-05-02T22:15:09","slug":"igm-drawing","status":"publish","type":"post","link":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/2025\/05\/02\/igm-drawing\/","title":{"rendered":"IgM Drawing"},"content":{"rendered":"\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-rt.googleusercontent.com\/docsz\/AD_4nXeCEOhm2vCevjy4vzAUYoVJ96VlZSzdsC-1dWyZrNlEzXBOP1cxKJ3XGPY04hlJ0-Nu5A7opHeiEGGhVbnDq4YklEffsYR98WWU056SNTM0Z10UgwMhnmpzbzmuH-iWHsQ8nrgLuA?key=yecHVHZa2mwRLgHln5uB890V\" alt=\"\" \/><\/figure>\n\n\n\n<p>This diagram illustrates the structure of the membrane-bound IgM (B-cell receptor). The antigen-recognition Fab regions, including the variable regions, extend outward to interact with antigens. The constant regions provide structural stability and aid in signal transduction. The receptor is anchored to the B-cell membrane via membrane-spanning domains, ensuring its proper localization. Glycosylation sites are also present, which play a role in stability and function. Unlike soluble pentameric IgM, which exists as a secreted antibody forming a five-unit structure with a J-chain, membrane-bound IgM remains monomeric and functions as part of the B-cell signaling complex.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This diagram illustrates the structure of the membrane-bound IgM (B-cell receptor). The antigen-recognition Fab regions, including the variable regions, extend outward to interact with antigens. The constant regions provide structural stability and aid in signal transduction. The receptor is anchored&#8230; <a class=\"more-link\" href=\"https:\/\/sites.wp.odu.edu\/catieg-immunology\/2025\/05\/02\/igm-drawing\/\">Continue Reading &rarr;<\/a><\/p>\n","protected":false},"author":30714,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","wds_primary_category":0},"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/posts\/194"}],"collection":[{"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/users\/30714"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/comments?post=194"}],"version-history":[{"count":1,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/posts\/194\/revisions"}],"predecessor-version":[{"id":195,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/posts\/194\/revisions\/195"}],"wp:attachment":[{"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/media?parent=194"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/categories?post=194"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/catieg-immunology\/wp-json\/wp\/v2\/tags?post=194"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}