There are several ethical issues that require our attention in the field of bio-cybersecurity. The work in this area involves defending biological systems and biotechnologies from malware and hacking attempts. The potential for bad actors to abuse biotechnology is one of the most important issues. Cybercriminals may use cyberattacks to acquire private information or control biological systems to their advantage. Unintended effects, such as the unintentional release of genetically modified organisms into the environment, are another ethical issue to take into account. Strong protections and protocols must be put in place immediately in order to reduce these dangers. Ultimately, ethical issues in bio-cybersecurity must be addressed to ensure ethical and secure technology use.