{"id":222,"date":"2024-12-12T21:48:09","date_gmt":"2024-12-12T21:48:09","guid":{"rendered":"https:\/\/sites.wp.odu.edu\/elayola\/?p=222"},"modified":"2024-12-12T22:19:31","modified_gmt":"2024-12-12T22:19:31","slug":"draw-igm","status":"publish","type":"post","link":"https:\/\/sites.wp.odu.edu\/elayola\/2024\/12\/12\/draw-igm\/","title":{"rendered":"Draw IgM"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><a href=\"http:\/\/sites.wp.odu.edu\/elayola\/wp-content\/uploads\/sites\/37939\/2024\/12\/Screenshot-2024-12-12-171844.png\"><img loading=\"lazy\" decoding=\"async\" width=\"697\" height=\"551\" src=\"http:\/\/sites.wp.odu.edu\/elayola\/wp-content\/uploads\/sites\/37939\/2024\/12\/Screenshot-2024-12-12-171844.png\" alt=\"\" class=\"wp-image-238\" srcset=\"https:\/\/sites.wp.odu.edu\/elayola\/wp-content\/uploads\/sites\/37939\/2024\/12\/Screenshot-2024-12-12-171844.png 697w, https:\/\/sites.wp.odu.edu\/elayola\/wp-content\/uploads\/sites\/37939\/2024\/12\/Screenshot-2024-12-12-171844-300x237.png 300w, https:\/\/sites.wp.odu.edu\/elayola\/wp-content\/uploads\/sites\/37939\/2024\/12\/Screenshot-2024-12-12-171844-600x474.png 600w\" sizes=\"(max-width: 697px) 100vw, 697px\" \/><\/a><\/figure>\n\n\n\n<p>This drawing replicates the cryo-electron microscopy molecule of immunoglobulin M (IgM). In<br>this model, the different aspects of what makes the immunoglobulin are represented in different<br>colors to make it easier to see how they interact and intertwine. It contains two kinds of chains; a<br>heavy chain that is represented by the \u201c\u03bc\u201d micro symbol and a light chain represented by the \u201c\u03ba\u201d<br>kappa symbol. Along with the two chains, there are constant portions where the immunoglobulin<br>does not contain antigen-binding domains and variable portions that are variable and responsible<br>for binding to antigens. There are also 14 sites of glycosylation with their location shown in<br>purple. The cryo-electron microscopy structure is a much more defined and detailed model of the<br>IgM. The structure of the cryo-em molecule is more dynamically flexible than the soluble<br>pentameric IgM. It also goes into great detail to help visualize the native state of the IgM,<br>whereas the pentameric structure is a model of the IgM in a stable state. With the pentameric<br>IgM model, you can properly view the different components that make up the structure but it<br>does not accurately represent how the structure is interacting with the different components of<br>the IgM itself<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This drawing replicates the cryo-electron microscopy molecule of immunoglobulin M (IgM). Inthis model, the different aspects of what makes the immunoglobulin are represented in differentcolors to make it easier to see how they interact and intertwine. It contains two kinds&#8230; <a class=\"more-link\" href=\"https:\/\/sites.wp.odu.edu\/elayola\/2024\/12\/12\/draw-igm\/\">Continue Reading &rarr;<\/a><\/p>\n","protected":false},"author":28407,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","wds_primary_category":0},"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/posts\/222"}],"collection":[{"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/users\/28407"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/comments?post=222"}],"version-history":[{"count":2,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/posts\/222\/revisions"}],"predecessor-version":[{"id":239,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/posts\/222\/revisions\/239"}],"wp:attachment":[{"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/media?parent=222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/categories?post=222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.wp.odu.edu\/elayola\/wp-json\/wp\/v2\/tags?post=222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}