BRCA2 gene participates in repairing radiation-induced breaks in double-stranded DNA
If individuals carry a BRCA2 gene mutation it can lead to increased risk of breast and ovarian cancer.
A genetic sequence data bank.
Homo Sapiens CF transmembrane conductance regulator (CFTR), RefSeqGene (LRG_663) on chromosome 7
“It is a membrane protein belonging to the ABC transporter family functioning as a chloride/anion channel in epithelial cells around the body” ( Meng X, Clews J, Kargas V, Wang X, Ford C, 2017).
Cystic fibrosis
Chromosome 7
Papio anubis (olive baboon)
Homo sapiens 0 percent GAP and for the Papio anubis 1 percent GAP
GAPS are the pieces left behind trying to create aligned protein or DNA sequences.
Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome
My guess is that different companies did the same sequencing.
cDNA is complimentary DNA which is created through reverse transcriptase.
Homo sapiens partial HBB gene for hemoglobin beta chain, exon 1, isolate 04593664
3
Frames 1 & 3
Yes
Can help to identify potential mutations and disease
the one thing I already knew was a little bit about how BLAST works
the thing I learned that was cool was ExPASy’s SIM program
Work Cited
Meng X, Clews J, Kargas V, Wang X, Ford C. The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability. Cell Mol Life Sci. 2017 Jan;74(1):23-38. doi: 10.1007/s00018-016-2386-8. Epub 2016 Oct 12. PMID: 27734094; PMCID: PMC5209436.
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