Brandon Osgood's ePortfolio

Genome Assignment

Genomics Assignment 

  1. Chromosome 13
  2. Chromosome 13 contains approximately 800 genes
  3.  And over 110 million base pairs 
  4. BRCA2
  5. BRCA2 gene participates in repairing radiation-induced breaks in double-stranded DNA
  6. If individuals carry a BRCA2 gene mutation it can lead to increased risk of breast and ovarian cancer.
  7. A genetic sequence data bank. 
  8. Homo Sapiens CF transmembrane conductance regulator (CFTR), RefSeqGene (LRG_663) on chromosome 7
  9. “It is a membrane protein belonging to the ABC transporter family functioning as a chloride/anion channel in epithelial cells around the body” ( Meng X, Clews J, Kargas V, Wang X, Ford C, 2017).
  10.  Cystic fibrosis 
  11. Chromosome 7
  12. Papio anubis (olive baboon)
  13. Homo sapiens 0 percent GAP and for the Papio anubis 1 percent GAP
  14. GAPS are the pieces left behind trying to create aligned protein or DNA sequences.
  15. Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome
  16. My guess is that different companies did the same sequencing.
  17. cDNA is complimentary DNA which is created through reverse transcriptase.
  18. Homo sapiens partial HBB gene for hemoglobin beta chain, exon 1, isolate 04593664
  19. 3
  20. Frames 1 & 3
  21. Yes
  22. Can help to identify potential mutations and disease
  23. fibroblast growth factor receptor 3 [Homo sapiens]
  24. the one thing I already knew was a little bit about how BLAST works 
  25. the thing I learned that was cool was ExPASy’s SIM program

Work Cited

  1. Meng X, Clews J, Kargas V, Wang X, Ford C. The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability. Cell Mol Life Sci. 2017 Jan;74(1):23-38. doi: 10.1007/s00018-016-2386-8. Epub 2016 Oct 12. PMID: 27734094; PMCID: PMC5209436.

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This entry was posted on December 11, 2020 by .