Chemical processes have been a cornerstone of the industrial evolution and societal progress. The development of sustainable chemical processes using green chemistry concepts can minimize resource use and environmental impacts. The Biomass (bio microbial advanced separation systems) Research Laboratory at Old Dominion University studies innovative sustainable chemical processes and ways to restrict the use of toxic and corrosive chemicals. The key objective is to develop sustainable chemical processes and products from waste and cultivated biomass using a systems approach that results in zero waste, high energy efficiency, zero toxicity, and minimal impact over the life cycle of the resulting bioproducts.